Format Your USB Drive as NTFS
USB drives are very common these days. They come in a variety of sizes and shapes and almost everyone uses one. USB drives are mostly formatted with the FAT or FAT32 filesystem. This is because traditionally USB drives had smaller capacity and by using NTFS on them we had more to loose than gain because of the greater overhead accompanying the use of NTFS. As the drives grew larger in size this has changed.
The single biggest reason that is alone enough to persuade you to use NTFS on USB drive is if you want to handle large files. If you have ever transferred a large ISO file you now what I mean. FAT does not support files larger than 4GB. In addition there are other benefits of using NTFS like encryption, per file and folder permissions, compression etc.
That said there are certain disadvantages of using NTFS as well, for one there are frequent writes to the disk and thus performance degrades a little but generally wouldn’t be noticeable for our purposes.